Fig. 1 · Structure
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AH23848
Thromboxane A2 receptor Blocker
AH23848 is a competitive antagonist of the thromboxane A2 receptor, exhibiting an IC50 value of 50 nM in human targets. This compound demonstrates effective oral bioavailability and a prolonged duration of action, making it valuable for research on cardiovascular diseases and thrombosis. Its ability to inhibit thromboxane A2 signaling highlights its potential utility in studying platelet function and related pathological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 81443-73-4 |
| Applications | Thromboxane A2 receptor Blocker |
| Formula | C29H35NO5 |
| Molecular Weight | 477.60 |
| SMILES | C(C/C=C\CCC(O)=O)[C@H]1[C@@H](C(=O)C[C@H]1OCC2=CC=C(C=C2)C3=CC=CC=C3)N4CCOCC4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.