Fig. 1 · Structure

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AHR-5333 (mandelate)

Cat. No. A76461 CAS 128766-12-1

5-Lipoxygenase Inhibitor

AHR-5333 (mandelate) is a selective inhibitor of 5-lipoxygenase, targeting human blood neutrophils. This compound demonstrates robust and sustained activity in vivo, particularly in models of immediate hypersensitivity in rats and guinea pigs. AHR-5333 (mandelate) is valuable for research applications exploring inflammatory responses and allergic reactions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 128766-12-1
Applications 5-Lipoxygenase Inhibitor
Formula C38H41F2NO7
Molecular Weight 661.73
SMILES
O=C(C(C1=CC=CC=C1)O)O.O=C(C)C2=CC=C(C(OC)=C2)OCCCN3CCC(C(C4=CC=C(C=C4)F)(C5=CC=C(C=C5)F)O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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