Fig. 1 · Structure
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AHR activator 1
Cat. No.
A73177
CAS
352346-46-4
Endogenous Metabolite
AHR Activator 1 is an aryl hydrocarbon receptor (AHR) activator that modulates fibroblast growth factor-2 (FGF2)-induced branching morphogenesis. It functions by inhibiting AHR signaling, thereby preventing cellular branch formation. Additionally, AHR Activator 1 interacts with dissociated linkers, highlighting their significance in the inhibitory effects of AHR agonists on branching. This compound is valuable for studying mammary gland morphogenesis and understanding the mechanisms underlying FGF-induced invasion.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 352346-46-4 |
| Applications | Endogenous Metabolite |
| Formula | C14H8Cl2N2O |
| Molecular Weight | 291.13 |
| SMILES | ClC1=CC=C(C(Cl)=C1)C2=NC(C3=CC=CC=C3)=NO2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.