Fig. 1 · Structure
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Ajmalicine hydrochloride
Adrenoceptor Inhibitor
Ajmalicine hydrochloride, primarily an adrenoceptor inhibitor, exhibits potent adrenolytic activity by preferentially blocking α1-adrenoceptors. This compound functions as a reversible, non-competitive inhibitor of nicotine receptors, with an IC50 of 72.3 μM. Ajmalicine hydrochloride is utilized in research related to antihypertensive effects, serpentine pathways, and sedative properties, providing insights into cardiovascular and neurological applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 4373-34-6 |
| Applications | Adrenoceptor Inhibitor |
| Formula | C21H25ClN2O3 |
| Molecular Weight | 388.89 |
| Synonyms | Raubasine hydrochloride |
| SMILES | O=C(C1=CO[C@@H](C)[C@](CN2CC3)([H])[C@]1([H])C[C@@]2([H])C4=C3C5=CC=CC=C5N4)OC.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.