Fig. 1 · Structure
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Ajmalicine
Adrenoceptor Inhibitor
Ajmalicine is a selective adrenoceptor inhibitor that primarily targets the α1-adrenoceptor, exhibiting potent adrenolytic activity. With an IC50 of 72.3 μM, it serves as a reversible, non-competitive inhibitor of nicotine receptors. Ajmalicine is utilized in research for its potential anti-hypertensive properties as well as its sedative effects, making it valuable for studies related to cardiovascular and neurological applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 483-04-5 |
| Applications | Adrenoceptor Inhibitor |
| Formula | C21H24N2O3 |
| Molecular Weight | 352.43 |
| Synonyms | Raubasine |
| SMILES | O=C(C1=CO[C@@H](C)[C@](CN2CC3)([H])[C@]1([H])C[C@@]2([H])C4=C3C5=CC=CC=C5N4)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.