AL-12180 is a potent and selective FP-receptor agonist, exhibiting a Ki of 143 nM. This compound effectively stimulates the mobilization of intracellular Ca2+ in human trabecular meshwork (h-TM) and cardiac muscle (h-CM) cells, demonstrating EC50 values of 111 nM and 11 nM, respectively. AL-12180 is valuable for research applications investigating FP-receptor signaling pathways and related physiological processes.
AL-12180 is a potent and selective FP-receptor agonist, exhibiting a Ki of 143 nM. This compound effectively stimulates the mobilization of intracellular Ca2+ in human trabecular meshwork (h-TM) and cardiac muscle (h-CM) cells, demonstrating EC50 values of 111 nM and 11 nM, respectively. AL-12180 is valuable for research applications investigating FP-receptor signaling pathways and related physiological processes.
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