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AL-12180

FP-receptor Agonist

AL-12180 is a potent and selective FP-receptor agonist, exhibiting a Ki of 143 nM. This compound effectively stimulates the mobilization of intracellular Ca2+ in human trabecular meshwork (h-TM) and cardiac muscle (h-CM) cells, demonstrating EC50 values of 111 nM and 11 nM, respectively. AL-12180 is valuable for research applications investigating FP-receptor signaling pathways and related physiological processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	748816-43-5
Applications	FP-receptor Agonist
Formula	C₂₁H₂₇ClO₆
Molecular Weight	410.89
SMILES	O=C(CC/C=C\CC[C@@H]1[C@H](OC[C@@H]1O)/C=C/[C@H](COC2=CC=CC(Cl)=C2)O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.