Fig. 1 · Structure
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AL284
AChE1 Inhibitor
AL284 is a potent inhibitor of Anopheles gambiae acetylcholinesterase 1 (AgAChE1), targeting key residues Tyr489Ag and Trp441Ag within the enzyme structure. This compound demonstrates significant biological activity in disrupting neurotransmitter breakdown, which is critical for the survival of disease-transmitting mosquitoes. AL284 is valuable for research applications focused on controlling mosquito populations and studying vector-borne diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2270876-07-6 |
| Applications | AChE1 Inhibitor |
| Formula | C26H35N3O3 |
| Molecular Weight | 437.57 |
| SMILES | CCN1CCN(CC1)C2CCN(CC2)C(COC3=CC=C(C=C3)C4=CC=C(C=C4)OC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.