Ald-CH2-PEG3-azide is a cleavable polyethylene glycol (PEG)-based linker designed for use in antibody-drug conjugates (ADCs) and proteolysis-targeting chimera (PROTAC) synthesis. This compound features an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-bearing molecules or DBCO/BCN groups. Its versatile chemistry facilitates the development of ADCs and PROTACs, making it invaluable for drug delivery and targeted therapeutic applications in chemical research.
Ald-CH2-PEG3-azide is a cleavable polyethylene glycol (PEG)-based linker designed for use in antibody-drug conjugates (ADCs) and proteolysis-targeting chimera (PROTAC) synthesis. This compound features an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-bearing molecules or DBCO/BCN groups. Its versatile chemistry facilitates the development of ADCs and PROTACs, making it invaluable for drug delivery and targeted therapeutic applications in chemical research.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
