Ald-Ph-amido-PEG11-C2-NH2

Catalog No.: A43102
ADC Linker
Ald-Ph-amido-PEG11-C2-NH2 is a non-cleavable 11-unit polyethylene glycol (PEG) linker designed for use in antibody-drug conjugate (ADC) synthesis. This versatile linker facilitates the stable attachment of cytotoxic agents to antibodies, enhancing the therapeutic efficacy of ADCs while minimizing systemic toxicity. Its design is optimized for applications in targeted cancer therapy research, allowing for precise drug delivery to malignant tissues.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAld-Ph-amido-PEG11-C2-NH2 is a non-cleavable 11-unit polyethylene glycol (PEG) linker designed for use in antibody-drug conjugate (ADC) synthesis. This versatile linker facilitates the stable attachment of cytotoxic agents to antibodies, enhancing the therapeutic efficacy of ADCs while minimizing systemic toxicity. Its design is optimized for applications in targeted cancer therapy research, allowing for precise drug delivery to malignant tissues.
Product Information
Catalog NumA43102
FormulaC32H56N2O13
Molecular Weight676.79
CAS Number1337889-01-6
SMILESO=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN)C1=CC=C(C=O)C=C1
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