Ald-Ph-amido-PEG4-propargyl is a non-cleavable polyethylene glycol (PEG) linker designed for antibody-drug conjugate (ADC) synthesis. This reagent features an alkyne group that enables its use in click chemistry, specifically the copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its application facilitates the stable attachment of therapeutic agents to antibodies, enhancing the efficacy of targeted cancer therapies.
Ald-Ph-amido-PEG4-propargyl is a non-cleavable polyethylene glycol (PEG) linker designed for antibody-drug conjugate (ADC) synthesis. This reagent features an alkyne group that enables its use in click chemistry, specifically the copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its application facilitates the stable attachment of therapeutic agents to antibodies, enhancing the efficacy of targeted cancer therapies.
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