Fig. 1 · Structure
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Ald-Ph-PEG2-NH-Boc
PROTAC Linker
Ald-Ph-PEG2-NH-Boc is a PEG-based linker designed specifically for PROTAC (Proteolysis Targeting Chimera) applications. This compound facilitates the synthesis of PROTACs by providing a flexible and stable connection between the target protein and the E3 ligase. Its PEG moiety enhances solubility and improves pharmacokinetic properties, making it an essential tool for researchers investigating targeted protein degradation pathways and related therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1807503-90-7 |
| Applications | PROTAC Linker |
| Formula | C19H28N2O6 |
| Molecular Weight | 380.44 |
| SMILES | O=C(OC(C)(C)C)NCCOCCOCCNC(C1=CC=C(C=O)C=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.