Fig. 1 · Structure
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Aldose reductase-IN-2
AR Inhibitor
Aldose reductase-IN-2 is a potent inhibitor of aldose reductase (AR), a key enzyme involved in the polyol pathway associated with diabetic complications. This compound exhibits significant antioxidation capacity, contributing to its effectiveness in reducing oxidative stress. Aldose reductase-IN-2 is valuable for research applications focused on the treatment of diabetes-related complications and offers potential insights into therapeutic strategies for managing such conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1687735-82-5 |
| Applications | AR Inhibitor |
| Formula | C25H28N4O5 |
| Molecular Weight | 464.51 |
| SMILES | O=C(NCCCNC([C@H](NC(C)=O)COCC1=CC=CC=C1)=O)/C(C#N)=C/C2=CC=C(O)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.