Alectinib Hydrochloride

Catalog No.: A18000

ALK inhibitor

Alectinib Hydrochloride

Alectinib Hydrochloride Chemical Structure

CAS NO. 1256589-74-8

Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively.

Availability: In stock

Package Price Qty
5 mg
$65.00
10 mg
$112.00
50 mg
$331.00
100 mg
$662.00
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Biological Activity

Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.26 mL 96.32 mL 192.65 mL
0.5 mM 3.85 mL 19.26 mL 38.53 mL
1 mM 1.93 mL 9.63 mL 19.26 mL
5 mM 0.39 mL 1.93 mL 3.85 mL

*The above data is based on the productmolecular weight 519.08. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18000
Actions Inhibitor
M. Wt 519.08
Formula C30H35ClN4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1256589-74-8
Synonyms CH5424802 Hydrochloride, CH 5424802, CH-5424802; RO5424802 Hydrochloride, RO 5424802, RO-5424802; AF-802 Hydrochloride,
SMILES [H]Cl.N#CC1=CC2=C(C3=C(N2)C(C)(C4=CC(N5CCC(CC5)N6CCOCC6)=C(C=C4C3=O)CC)C)C=C1

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