Fig. 1 · Structure
Documents & Downloads
ALK-5-IN-1
Cat. No.
A84882
CAS
1018953-58-6
ALK-5 Inhibitor
ALK-5-IN-1 is a selective inhibitor of ALK-5 (activin receptor-like kinase 5), a critical receptor in the TGF-beta signaling pathway. This compound demonstrates significant anti-fibrotic and anti-cancer activity, making it a valuable tool in preclinical studies investigating fibrosis-related conditions and tumor progression. It is suitable for researchers exploring the roles of TGF-beta signaling in diverse biological processes and therapeutic strategies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1018953-58-6 |
| Applications | ALK-5 Inhibitor |
| Formula | C18H16N4S |
| Molecular Weight | 320.41 |
| SMILES | CC1=CC=CC(N2N=CC(CC)=C2C(S3)=CC4=C3C=CN=C4)=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.