Fig. 1 · Structure
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ALK5-IN-34
ALK5 Inhibitor
ALK5-IN-34 is a selective inhibitor of activin receptor-like kinase 5 (ALK5), exhibiting potent activity with an IC50 value of ≤10 nM. This compound effectively reduces tumor proliferation, making it a valuable tool for research on proliferative diseases, including various cancer types. ALK5-IN-34 may facilitate investigations into the mechanisms underlying cancer progression and therapeutic interventions targeting the ALK5 pathway.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2785430-90-0 |
| Applications | ALK5 Inhibitor |
| Formula | C23H23N7O |
| Molecular Weight | 413.48 |
| SMILES | CC1=CC=CC2=C(NC3=NC(NC4=CC=CC(N5CCOCC5)=C4)=NC=C3)C=NN=C12 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.