Fig. 1 · Structure

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ALK5-IN-80

Cat. No. A84886 CAS 3039952-63-8

ALK5 Inhibitor

ALK5-IN-80 is a selective inhibitor of ALK5, exhibiting an IC50 value of 3.7 nM. This compound effectively antagonizes ALK5 signaling pathways, making it a valuable tool for cancer research. Its ability to selectively inhibit ALK5 activity allows for investigations into the role of this pathway in oncogenesis and tumor progression.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3039952-63-8
Applications ALK5 Inhibitor
Formula C21H18FN7O2S
Molecular Weight 451.48
SMILES
O=C(N)C1=C(C2=CC(C(C)=O)=CN2)SC(N(C3CC3)C4=CN(N=C4)C5=C(F)C=NC=C5)=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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