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ALK5-IN-85

Name: ALK5-IN-85
Brand: Adooq Bioscience
SKU: A84897
Availability: OutOfStock

Cat. No. A84897 CAS 2766583-86-0

ALK5 Inhibitor

ALK5-IN-85 is an inhibitor of TGFβRI (ALK5) with an IC50 of less than 100 nM. This compound exhibits significant potential in the study of respiratory diseases such as idiopathic pulmonary fibrosis, asthma, chronic obstructive pulmonary disease (COPD), and lung cancer. Additionally, ALK5-IN-85 may be applicable in researching dermal and ocular fibrotic conditions, making it a valuable tool for understanding and targeting fibrotic pathways in various therapeutic areas.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2766583-86-0
Applications	ALK5 Inhibitor
Formula	C₃₃H₃₂FN₇O₃
Molecular Weight	593.65
SMILES	O=C(C1=CC(NC(CN2N=C(C(C3=C4C=CC=CC4=NC=C3)=C2)C5=CC=CC(C)=N5)=O)=CC(F)=C1)OCCN6CCNCC6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.