ALLO-2

Catalog No.: A18698

Smo mutant antagonist

ALLO-2

ALLO-2 Chemical Structure

CAS NO. 1357350-60-7

ALLO-2 is a potent drug-resistant Smoothened (Smo) mutant antagonist that inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.

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Package Price Qty
5 mg
$320.00
10 mg
$520.00
50 mg
$1,620.00
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Biological Activity

ALLO-2 is a potent drug-resistant Smoothened (Smo) mutant antagonist that inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.93 mL 134.65 mL 269.31 mL
0.5 mM 5.39 mL 26.93 mL 53.86 mL
1 mM 2.69 mL 13.47 mL 26.93 mL
5 mM 0.54 mL 2.69 mL 5.39 mL

*The above data is based on the productmolecular weight 371.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18698
Actions Antagonist
M. Wt 371.32
Formula C18H12F3N5O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1357350-60-7
Synonyms ALLO2, ALLO 2
SMILES FC(F)(OC1=CC=C(C=C1)C2=NC(NC3=CC4=C(C=C3)NN=C4)=NC=C2)F

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