Allotrap 07

Catalog No.: A65035
HLA-B7-Derived Peptide
Allotrap 07 is a synthetic peptide derived from residues 75-84 of the HLA-B7 molecule, a class I major histocompatibility complex (MHC) protein. This peptide is known for its ability to promote donor-specific tolerance in rat cardiac allografts when used in conjunction with Cyclosporin A, leading to a significant extension of graft survival. Allotrap 07 is a valuable tool for researchers exploring mechanisms of immune tolerance and transplant biology.
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAllotrap 07 is a synthetic peptide derived from residues 75-84 of the HLA-B7 molecule, a class I major histocompatibility complex (MHC) protein. This peptide is known for its ability to promote donor-specific tolerance in rat cardiac allografts when used in conjunction with Cyclosporin A, leading to a significant extension of graft survival. Allotrap 07 is a valuable tool for researchers exploring mechanisms of immune tolerance and transplant biology.
Product Information
Catalog NumA65035
FormulaC53H90N20O16
Molecular Weight1263.41
CAS Number151232-75-6
SequenceArg-Glu-Ser-Leu-Arg-Asn-Leu-Arg-Gly-Tyr
Sequence shorteningRESLRNLRGY
SMILES[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC1=CC=C(O)C=C1)C(O)=O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CC(N)=O)=O)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCC(O)=O)=O)CO)=O)CC(C)C)=O)CCCNC(=N)N
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