Fig. 1 · Structure
Documents & Downloads
Aloe-emodin-8-O-β-D-glucopyranoside
Phosphatase Inhibitor
Aloe-emodin-8-O-β-D-glucopyranoside is a moderate inhibitor of human protein tyrosine phosphatase 1B (hPTP1B), exhibiting an IC50 of 26.6 μM. This compound, derived from Saussurea lappa, demonstrates significant biological activity relevant to the regulation of signaling pathways involved in insulin signaling and glucose homeostasis. It serves as a valuable tool for researchers investigating the role of phosphatase inhibition in metabolic disorders and related therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 33037-46-6 |
| Applications | Phosphatase Inhibitor |
| Formula | C21H20O10 |
| Molecular Weight | 432.38 |
| SMILES | O=C(C1=CC(CO)=CC(O)=C1C2=O)C3=C2C(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)CO)=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.