ALT-100 (Human IgG4)

ALT-100 (Human IgG4) is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically designed to target NAMPT. This antibody is engineered with a hybrid heavy chain comprising both human IgG1 and IgG4 regions, paired with a human kappa light chain. It exhibits a molecular weight of approximately 150 kDa. ALT-100 is applicable in the study of inflammatory and fibrotic diseases, where Human IgG4 (S228P) kappa serves as the appropriate isotype control. For other research applications, Human IgG1 kappa is recommended as the isotype control. This product is essential for researchers focusing on the modulation of NAMPT activity and its implications in various disease states.

In Stock

Biological Activity

Target & Activity

NAMPT

Product Details

Manufacturer Adooq Bioscience

Storage

Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Customer Questions
Biosimilar antibodies are research-grade recombinant antibodies designed to closely resemble approved therapeutic antibodies in terms of amino acid sequence, structural characteristics, and biological activity. These antibodies are generated using recombinant expression technologies and retain the same variable regions as their corresponding reference therapeutics, thereby preserving target specificity and binding affinity. Owing to these properties, biosimilar antibodies serve as reliable and cost-effective research reagents for applications in drug discovery, pharmacological studies, and basic biomedical research. Research-grade biosimilar antibodies have been successfully expressed and functionally validated against a wide range of widely studied targets. These antibodies can be directly utilized as positive control reagents in drug discovery programs, as well as reference tools for rapid verification of the biological functions of target proteins in biochemical and cellular assays.
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