Fig. 1 · Structure

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Aluminum phthalocyanine chloride

Photosensitizer

Aluminum phthalocyanine chloride is a photosensitizer that demonstrates significant inhibitory effects on the parasite Leishmania amazonensis, the agent responsible for cutaneous leishmaniasis, through light-mediated cytolysis. This compound induces morphological changes and cytolysis in isolated amastigotes, while higher concentrations and light intensities are necessary to affect mammalian cells. Additionally, aluminum phthalocyanine chloride effectively lyses parasites within infected J774 macrophages, making it a valuable tool for studying leishmaniasis and exploring potential therapeutic avenues.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 14154-42-8
Applications Photosensitizer
Formula C32H16AlClN8
Molecular Weight 574.96
Synonyms AlClPc
SMILES
[Cl-][Al+3]12([N](C(C3=CC=CC=C43)=N5)=C4N=C6C7=CC=CC=C87)[N-]6C8=NC9=[N]1C(C%10=CC=CC=C9%10)=NC%11=C(C=CC=C%12)C%12=C5[N-]2%11

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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