Fig. 1 · Structure
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ALX-5407 hydrochloride
GlyT1 Inhibitor
ALX-5407 hydrochloride is a selective inhibitor of the glycine transporter GlyT1, exhibiting a potent IC50 value of 3 nM. This compound is particularly valuable in the study of N-methyl-D-aspartate receptor function and has potential applications in schizophrenia research. Its oral bioavailability allows for convenient administration in vivo, making it an important tool for exploring glycine modulation in neurological studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 200006-08-2 |
| Applications | GlyT1 Inhibitor |
| Formula | C24H25ClFNO3 |
| Molecular Weight | 429.91 |
| Synonyms | (R)-NFPS hydrochloride |
| SMILES | FC1=CC=C([C@H](OC2=CC=C(C3=CC=CC=C3)C=C2)CCN(C)CC(O)=O)C=C1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.