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Form	MW
ALX-5407 This page	393.45
ALX-5407 hydrochloride	429.91

ALX-5407

GlyT Inhibitor

ALX-5407 (R)-NFPS is a selective, orally active inhibitor of the glycine transporter GlyT1, exhibiting an IC50 value of 3 nM. This compound plays a crucial role in the study of N-methyl-D-aspartate (NMDA) receptor function and has potential applications in schizophrenia research. Its targeted action on GlyT1 makes ALX-5407 a valuable tool for investigating synaptic transmission and the modulation of glutamatergic signaling pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	571147-18-7
Applications	GlyT Inhibitor
Formula	C₂₄H₂₄FNO₃
Molecular Weight	393.45
Synonyms	(R)-NFPS
SMILES	OC(CN(C)CC[C@H](C1=CC=C(C=C1)F)OC2=CC=C(C3=CC=CC=C3)C=C2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.