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AM12

Catalog No.: A68814
TRP Channel Activator
AM12 is a selective TRP channel activator that specifically inhibits Lanthanide-evoked TRPC5 activity, demonstrating an IC50 value of 0.28 μM. This compound is valuable for research investigating the modulation of TRPC5 channels and their role in calcium signaling pathways. AM12 is ideal for studies focused on cellular responses to TRP channel activation and the physiological implications in various biological systems.
AM12 2387510-84-9 TRP Channel Activator
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10mg
$4,015.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAM12 is a selective TRP channel activator that specifically inhibits Lanthanide-evoked TRPC5 activity, demonstrating an IC50 value of 0.28 μM. This compound is valuable for research investigating the modulation of TRPC5 channels and their role in calcium signaling pathways. AM12 is ideal for studies focused on cellular responses to TRP channel activation and the physiological implications in various biological systems.
Product Information
Catalog NumA68814
FormulaC15H9BrO5
Molecular Weight349.13
CAS Number2387510-84-9
SMILESO=C1C(O)=C(C2=CC=CC=C2Br)OC3=C1C(O)=CC(O)=C3
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Membrane Transporters-Ion Channels > TRP Channel