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AM432 sodium

CRTH2 Antagonist

AM432 sodium is a selective antagonist of the CRTH2 receptor, also known as DP2. This compound exhibits high potency in human whole blood eosinophil assays, particularly under prolonged incubation conditions. Additionally, AM432 sodium has shown favorable pharmacokinetic profiles in canine and murine models of inflammatory diseases, making it a valuable tool for research in immunology and inflammatory pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	1263409-34-2
Applications	CRTH2 Antagonist
Formula	C₂₉H₃₁N₂NaO₅
Molecular Weight	510.56
SMILES	O=C(O[Na])CC1=CC(C2=CC=C(C3=CC=C(OCC)N=C3)C=C2CN(C(C4CC4)=O)CC)=C(OC)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.