Amcinonide is a glucocorticoid receptor agonist that exhibits anti-inflammatory properties by inhibiting nitric oxide (NO) release with an IC50 of 3.38 nM. It effectively downregulates the expression of pro-inflammatory genes such as iNOS, TNF-α, and IL-1β in glial cells. Moreover, Amcinonide alters T cell populations by reducing T6+/Ia+ cells while increasing T6+/Ia- cells, leading to a selective decrease in Ia antigen expression. This compound is applicable in research related to eczematous dermatitis and the modulation of inflammatory responses.
Amcinonide is a glucocorticoid receptor agonist that exhibits anti-inflammatory properties by inhibiting nitric oxide (NO) release with an IC50 of 3.38 nM. It effectively downregulates the expression of pro-inflammatory genes such as iNOS, TNF-α, and IL-1β in glial cells. Moreover, Amcinonide alters T cell populations by reducing T6+/Ia+ cells while increasing T6+/Ia- cells, leading to a selective decrease in Ia antigen expression. This compound is applicable in research related to eczematous dermatitis and the modulation of inflammatory responses.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
