AMG-333

Catalog No.: A17182

TRPM8 Antagonist

AMG-333

AMG-333 Chemical Structure

CAS NO. 1416799-28-4

AMG-333 is a potent and selective TRPM8 Antagonist.

Availability: In stock

Package Price Qty
2 mg
$250.00
5 mg
$450.00
10 mg
$820.00
50 mg
$3,200.00
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Biological Activity

AMG-333 is a potent and selective TRPM8 Antagonist.
In vitro DMSO 81 mg/mL (178.68 mM)
Water Insoluble
Ethanol 81 mg/mL (178.68 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.06 mL 110.3 mL 220.59 mL
0.5 mM 4.41 mL 22.06 mL 44.12 mL
1 mM 2.21 mL 11.03 mL 22.06 mL
5 mM 0.44 mL 2.21 mL 4.41 mL

*The above data is based on the productmolecular weight 453.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17182
Actions Antagonist
CAS No. 1416799-28-4
Formula C20H12F5N3O4
M. Wt 453.32
Solubility DMSO
Purity >98%
Synonyms AMG333, AMG 333
SMILES O=C(O)C1=CN=C(C(N[[email protected]@H](C2=CC=C(OC(F)(F)F)C(F)=C2)C3=NC=CC=C3F)=O)C=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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