AMG-8718

Catalog No.: A14407

BACE1 inhibitor

AMG-8718

AMG-8718 Chemical Structure

CAS NO. 1215868-94-2

AMG-8718 is a potent and orally efficacious BACE1 inhibitor.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$600.00
25 mg
$1,200.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AMG-8718 is a potent and orally efficacious BACE1 inhibitor.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.6 mL 113.01 mL 226.02 mL
0.5 mM 4.52 mL 22.6 mL 45.2 mL
1 mM 2.26 mL 11.3 mL 22.6 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14407
Actions Inhibitor
M. Wt 442.44
Formula C25H19FN4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1215868-94-2
Synonyms AMG 8718, AMG8718
SMILES NC(OC1)=N[[email protected]@]21C3=CC(C4=CC=CN=C4F)=CC=C3OC5=NC=C(C#CC6(C)COC6)C=C52

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