AMG0347 is a potent antagonist of the transient receptor potential type V1 (TRPV1) channel. It effectively inhibits TRPV1 activation by heat (IC50 = 0.2 nM), protons (IC50 = 0.8 nM), and capsaicin (IC50 = 0.7 nM). This compound is useful for research applications related to nociception, pain pathways, and sensory neuron function.
AMG0347 is a potent antagonist of the transient receptor potential type V1 (TRPV1) channel. It effectively inhibits TRPV1 activation by heat (IC50 = 0.2 nM), protons (IC50 = 0.8 nM), and capsaicin (IC50 = 0.7 nM). This compound is useful for research applications related to nociception, pain pathways, and sensory neuron function.
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