Amiloride HCl

Name: Amiloride HCl
Brand: Adooq Bioscience
SKU: A10064
Rating: 100 (2 reviews)

Catalog No.: A10064

Na+ channel blocker

Product Citations (2)

Amiloride HCl Chemical Structure

CAS NO. 2016-88-8

Amiloride hydrochloride is a Na+ channel blocker, also inhibits TRPP3 channels and Na+/H+ exchanger (NHE).

Availability: In stock

Package	Price	Qty
200 mg	$40.00
500 mg	$60.00
10mM * 1mL in DMSO	$60.00
Custom Size	Get quote

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Products are for laboratory research use only. Not for human use. We do not sell to patients.

Adooq Products cited in reputable paper

Publications Citing Use of Adooq Amiloride HCl

Yu Y, .et al. Expression, Localization and Functional Activity of the Major Na+/H+ Exchange Isoforms Expressed in the Intestinal Cell Line Caco-2BBe, Cell Physiol Biochem, 2019, 52(5):1017-1038 PMID: 30977986
Thomas D. Williams, .et al. The physiological regulation of macropinocytosis during Dictyostelium growth and development, J Cell Sci, 2018, Mar 15; 131(6): jcs213736 PMID: 29440238

Biological Activity

Amiloride hydrochloride is a Na+ channel blocker, also inhibits TRPP3 channels and Na+/H+ exchanger (NHE).

Solubility *

In vitro	DMSO	49 mg/mL (184.15 mM)
	Water	6 mg/mL (22.54 mM)
	Ethanol	5 mg/mL (18.79 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	37.58 mL	187.9 mL	375.8 mL
0.5 mM	7.52 mL	37.58 mL	75.16 mL
1 mM	3.76 mL	18.79 mL	37.58 mL
5 mM	0.75 mL	3.76 mL	7.52 mL

*The above data is based on the productmolecular weight 266.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A10064
Actions	Blocker
CAS No.	2016-88-8
Formula	C6H9Cl2N7O
M. Wt	266.1
Purity	>98%
Synonyms	MK 870, Midamor, Colectril, Amipramizide, Guanamprazine hydrochloride
SMILES	C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.Cl
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.