Catalog No.
Product Name
Application
Product Information
Product Citation
-
Na+ channel blocker
Amiloride hydrochloride is a Na+ channel blocker, also inhibits TRPP3 channels and Na+/H+ exchanger (NHE).- Yu Y, .et al. , Cell Physiol Biochem, 2019, 52(5):1017-1038 PMID: 30977986
- Thomas D. Williams, .et al. , J Cell Sci, 2018, Mar 15; 131(6): jcs213736 PMID: 29440238
-
Na+/H+-exchange inhibitor
FR183998 free base is a potent Na+/H+-exchange inhibitor, with IC50s of 0.3 nM, 3.1 nM and 6.5 nM by measurement of pHi change in rat lymphocytes, rat and human platelets, respectively. -
Na+/H+ exchange inhibitor
Cariporide (HOE-642) is a selective Na+/H+ exchange inhibitor. -
NHE3 inhibitor
Tenapanor acts as an inhibitor of the sodium-proton exchanger NHE3. This antiporter protein is found in the kidney and intestines, and normally acts to regulate the levels of sodium absorbed and secreted by the body.- Mahdi Amiri, .et al. , Am J Physiol Cell Physiol, 2024, Mar 1;326(3):C829-C842 PMID: 38223928
- Kuniko Hunter, .et al. , Tissue Eng Part A, 2022, Nov 18 PMID: 36274231
- Xingjie Tan, .et al. , Authorea, 2022, May 25
- Kunyan Zhou, .et al. , Am J Physiol Cell Physiol, 2021, Sep 1;321(3):C471-C488 PMID: 34288721
- Qinghai Tan, .et al. , Br J Pharmacol, 2021, Mar;178(5):1018-1036 PMID: 33179259
- Y Liu, .et al. , Biochem Pharmacol, 2020, May 16;178:114040 PMID: 32422138
- Yu Y, .et al. , Cell Physiol Biochem, 2019, 52(5):1017-1038 PMID: 30977986
- Thammayon N, .et al. , Amino Acids, 2017, Apr;49(4):725-734 PMID: 27981415
- Charoenphandhu N, .et al. , Mol Cell Biochem, 2017, Mar;427(1-2):201-208 PMID: 27995414
- Jantarajit W, .et al. , Am J Physiol Cell Physiol, 2017, Jul 1;313(1):C118-C129 PMID: 28490422
-
NHE-1 inhibitor
Rimeporide (EMD-87580) is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1). -
Na+/H+ exchange inhibitor
Eniporide hydrochloride (EMD-96785 hydrochloride) is a potent Na+/H+ exchange inhibitor.
