Fig. 1 · Structure
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Amino-PEG3-CH2COOH
PROTAC Linker
Amino-PEG3-CH2COOH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (PROteolysis TArgeting Chimeras). This compound features an amino group that facilitates conjugation with targeting ligands and an acidic carboxylic group that enhances solubility. Amino-PEG3-CH2COOH is instrumental in the development of targeted protein degradation strategies, making it valuable for research in cancer therapeutics and other diseases involving aberrant protein levels.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 134978-99-7 |
| Applications | PROTAC Linker |
| Formula | C8H17NO5 |
| Molecular Weight | 207.22 |
| SMILES | O=C(O)COCCOCCOCCN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.