Fig. 1 · Structure
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Amino-PEG4-C2-amine
PROTAC Linkers
Amino-PEG4-C2-amine is a polyethylene glycol (PEG)-based linker consisting of four ethylene glycol units, specifically designed for use in PROTAC (proteolysis-targeting chimera) synthesis. Its primary mechanism involves facilitating the connection of target ligands to E3 ligase recruiters, enabling targeted protein degradation. This compound is essential for researchers developing novel therapeutics aimed at modulating protein levels in various biological pathways and disease states.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 68960-97-4 |
| Applications | PROTAC Linkers |
| Formula | C10H24N2O4 |
| Molecular Weight | 236.31 |
| SMILES | NCCOCCOCCOCCOCCN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.