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Amino-PEG4-Val-Cit-PAB-MMAE

Catalog No.: A41337
Cleavable ADC Linker
Amino-PEG4-Val-Cit-PAB-MMAE is a cleavable linker designed for use in the synthesis of antibody-drug conjugates (ADCs). This compound facilitates selective drug delivery by connecting antibodies to the cytotoxic agent MMAE, enhancing therapeutic efficacy while minimizing off-target effects. Its PEG4 moiety ensures improved solubility and stability, making it suitable for research applications in cancer therapy and targeted delivery systems.
Amino-PEG4-Val-Cit-PAB-MMAE 1492056-71-9 Cleavable ADC Linker
Grouped product items
Size Price Stock Qty
1mg
$110.00
In stock
5mg
$245.00
In stock
10mg
$410.00
In stock
25mg
$825.00
In stock
50mg
$1,355.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAmino-PEG4-Val-Cit-PAB-MMAE is a cleavable linker designed for use in the synthesis of antibody-drug conjugates (ADCs). This compound facilitates selective drug delivery by connecting antibodies to the cytotoxic agent MMAE, enhancing therapeutic efficacy while minimizing off-target effects. Its PEG4 moiety ensures improved solubility and stability, making it suitable for research applications in cancer therapy and targeted delivery systems.
Product Information
Catalog NumA41337
FormulaC69H115N11O17
Molecular Weight1370.71
CAS Number1492056-71-9
SMILESCN([C@@H]([C@@H](C)CC)[C@H](OC)CC(N1[C@H]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)CCC1)=O)C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCN)=O)=O)=O)C=C3)=O)C)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2

Antibody-drug Conjugates (ADC) > ADC Linker