Aminomethyltrioxsalen hydrochloride is a psoralen derivative that acts as a viral inactivator through nucleic acid intercalation. It effectively penetrates intact cells, allowing it to react with nucleic acid secondary structures in vivo while preserving the integrity of natural nucleoprotein tissues. Upon exposure to UV-A radiation, it crosslinks pyrimidine residues in viral nucleic acids, leading to inactivation of viruses. This reagent is valuable for research applications related to viral infections, including studies on dengue virus.
Aminomethyltrioxsalen hydrochloride is a psoralen derivative that acts as a viral inactivator through nucleic acid intercalation. It effectively penetrates intact cells, allowing it to react with nucleic acid secondary structures in vivo while preserving the integrity of natural nucleoprotein tissues. Upon exposure to UV-A radiation, it crosslinks pyrimidine residues in viral nucleic acids, leading to inactivation of viruses. This reagent is valuable for research applications related to viral infections, including studies on dengue virus.
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