Fig. 1 · Structure
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Amodiaquine
Antimalarial Agent
Amodiaquine is a 4-aminoquinoline antimalarial agent that functions primarily by inhibiting histamine N-methyltransferase. Additionally, it acts as a Nurr1 agonist, specifically binding to the Nurr1 ligand-binding domain with an EC50 of approximately 20 µM. Its anti-inflammatory properties make it a valuable tool for research in malaria treatment and inflammation-related studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 86-42-0 |
| Applications | Antimalarial Agent |
| Formula | C20H22ClN3O |
| Molecular Weight | 355.86 |
| Synonyms | Amodiaquin |
| SMILES | OC1=CC=C(NC2=CC=NC3=CC(Cl)=CC=C23)C=C1CN(CC)CC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.