Anafiltamig is a trivalent monoclonal antibody that targets CD79B, CD3E, and MS4A1. This innovative reagent features a humanized IgG1κ anti-CD79B component combined with a bispecific scFv fragment designed to engage CD3E and MS4A1. By simultaneously bridging T and B cells, Anafiltamig activates T cells, leading to the selective elimination of B cell tumors. This compound is particularly useful for research in B cell malignancies, including non-Hodgkin lymphoma.
Anafiltamig is a trivalent monoclonal antibody that targets CD79B, CD3E, and MS4A1. This innovative reagent features a humanized IgG1κ anti-CD79B component combined with a bispecific scFv fragment designed to engage CD3E and MS4A1. By simultaneously bridging T and B cells, Anafiltamig activates T cells, leading to the selective elimination of B cell tumors. This compound is particularly useful for research in B cell malignancies, including non-Hodgkin lymphoma.
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