Anagyrine hydrochloride is a quinolizidine alkaloid that serves as a desensitizer of nicotinic acetylcholine receptors (nAChR). It exhibits potent binding to muscarinic acetylcholine receptors with an IC50 value of 132 µM and a weaker interaction with nAChR at 2096 µM. This compound effectively desensitizes nAChR without requiring metabolic conversion, making it valuable for research involving cholinergic signaling and receptor function studies.
Anagyrine hydrochloride is a quinolizidine alkaloid that serves as a desensitizer of nicotinic acetylcholine receptors (nAChR). It exhibits potent binding to muscarinic acetylcholine receptors with an IC50 value of 132 µM and a weaker interaction with nAChR at 2096 µM. This compound effectively desensitizes nAChR without requiring metabolic conversion, making it valuable for research involving cholinergic signaling and receptor function studies.
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