Anagyrine is a quinolizidine alkaloid that acts as a desensitizer of nicotinic acetylcholine receptors (nAChR). It demonstrates binding affinity with IC50 values of 132 µM for muscarinic receptors and 2096 µM for nicotinic receptors, effectively modulating nAChR activity. This compound is utilized in research to study nAChR desensitization mechanisms and its implications in various neural and pharmacological contexts.
Anagyrine is a quinolizidine alkaloid that acts as a desensitizer of nicotinic acetylcholine receptors (nAChR). It demonstrates binding affinity with IC50 values of 132 µM for muscarinic receptors and 2096 µM for nicotinic receptors, effectively modulating nAChR activity. This compound is utilized in research to study nAChR desensitization mechanisms and its implications in various neural and pharmacological contexts.
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