Fig. 1 · Structure
Documents & Downloads
Anatibant hydrochloride
Bradykinin B2 Receptor Antagonist
Anatibant hydrochloride is a selective non-peptide antagonist of the bradykinin B2 receptor. It exhibits high affinity binding to recombinant B2 receptors in human, rat, and guinea pig models, with Ki values of 0.67 nM, 1.74 nM, and 1.37 nM, respectively. Notably, Anatibant hydrochloride is capable of crossing the blood-brain barrier, making it a valuable tool for investigating pathophysiological conditions related to brain injury and neuroinflammation.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 209788-45-4 |
| Applications | Bradykinin B2 Receptor Antagonist |
| Formula | C34H38Cl4N6O5S |
| Molecular Weight | 784.58 |
| Synonyms | LF 16-0687 hydrochloride; XY-2405 hydrochloride |
| SMILES | O=C(NCCCNC(C1=CC=C(C=C1)C(N)=N)=O)[C@H]2N(CCC2)S(=O)(C3=CC=C(C(COC4=C5N=C(C=C(C5=CC=C4)C)C)=C3Cl)Cl)=O.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.