Fig. 1 · Structure
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Andolast free base
cAMP-phosphodiesterase inhibitor
Andolast free base is a potent inhibitor of cAMP-phosphodiesterase, demonstrating an IC50 value of 50 μM. This compound exhibits anti-allergic properties and is primarily utilized in the research of asthma. Its ability to modulate cAMP levels makes it a valuable tool for studying mechanisms underlying allergic responses and respiratory conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 132640-22-3 |
| Applications | cAMP-phosphodiesterase inhibitor |
| Formula | C15H11N9O |
| Molecular Weight | 333.31 |
| Synonyms | CR 2039 free base; Dizolast free base |
| SMILES | O=C(C1=CC=C(C2=NN=NN2)C=C1)NC3=CC=C(C4=NN=NN4)C=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.