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Andolast

cAMP-phosphodiesterase inhibitor

Andolast is a specific inhibitor of cAMP-phosphodiesterase, demonstrating an IC50 value of 50 μM. With its ability to modulate cAMP levels, Andolast serves as an anti-allergic agent and is primarily utilized in research related to asthma. This compound offers valuable insights into the mechanisms underlying allergic responses and potential therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	143330-46-5
Applications	cAMP-phosphodiesterase inhibitor
Formula	C₁₅H₁₁N₉Na₂O
Molecular Weight	379.29
Synonyms	CR 2039; Dizolast
SMILES	O=C(C1=CC=C(C2=NN=NN2)C=C1)NC3=CC=C(C4=NN=NN4)C=C3.[Na].[Na]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.