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Andrastin B

Farnesyltransferase Inhibitor

Andrastin B is an inhibitor of protein farnesyltransferase, targeting the post-translational modification of proteins involved in cell signaling and proliferation. Its ability to disrupt farnesylation makes it a valuable tool for investigating pathways associated with cancer and other diseases. Andrastin B's unique androstane structure enhances its potential use in biochemical research, particularly in studies focused on targeted therapies and signal transduction mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	174232-43-0
Applications	Farnesyltransferase Inhibitor
Formula	C₂₈H₄₀O₇
Molecular Weight	488.61
SMILES	COC([C@]12[C@@]3([C@](C=C([C@]1(C(C(C2=O)C)=O)C)C)([H])[C@]4([C@](C(C)([C@H](CC4)OC(C)=O)C)([H])CC3)CO)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.