Fig. 1 · Structure

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Andrastin D

Farnesyltransferase Inhibitor

Andrastin D is a potent inhibitor of protein farnesyltransferase, an enzyme involved in post-translational modification of proteins that affect cell signaling and growth. With its characteristic androstane structure, Andrastin D exhibits significant biological activity by disrupting farnesylation, thereby influencing pathways associated with cancer cell proliferation and survival. This compound is valuable for researchers investigating therapeutic strategies targeting farnesyltransferase in oncological studies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 184432-08-4
Applications Farnesyltransferase Inhibitor
Formula C26H36O5
Molecular Weight 428.56
SMILES
COC([C@]12[C@@]3([C@](C=C([C@]1(C(O)=C(C2=O)C)C)C)([H])[C@]4([C@](C(C)(C(CC4)=O)C)([H])CC3)C)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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