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Anetumab

Anetumab is a monoclonal antibody specifically targeting mesothelin (MSLN), a well-recognized tumor-associated antigen prevalent in various malignant tumors. This antibody serves as a foundational component in the synthesis of Anetumab ravtansine, an antibody-drug conjugate (ADC) that selectively delivers cytotoxic agents to MSLN-expressing tumor cells. Anetumab is primarily utilized in research settings to investigate the therapeutic potential and targeting efficacy against mesothelin-positive malignancies.

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Product Details

Manufacturer Adooq Bioscience
CAS Number 1954758-84-9
Molecular Weight 143660
Synonyms Anti-MSLN Antibody

Storage

Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Customer Questions
Biosimilar antibodies are research-grade recombinant antibodies designed to closely resemble approved therapeutic antibodies in terms of amino acid sequence, structural characteristics, and biological activity. These antibodies are generated using recombinant expression technologies and retain the same variable regions as their corresponding reference therapeutics, thereby preserving target specificity and binding affinity. Owing to these properties, biosimilar antibodies serve as reliable and cost-effective research reagents for applications in drug discovery, pharmacological studies, and basic biomedical research. Research-grade biosimilar antibodies have been successfully expressed and functionally validated against a wide range of widely studied targets. These antibodies can be directly utilized as positive control reagents in drug discovery programs, as well as reference tools for rapid verification of the biological functions of target proteins in biochemical and cellular assays.
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