Angiogenesis

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  1. EGFR activator

    NSC 228155 is an activator of EGFR, binds to the extracellular region of EGFR and enhance tyrosine phosphorylation of EGFR.
  2. HIF activator

    ML-228 is an activator of the HIF signaling pathway, as demonstrated by HIF response element (HRE) reporter assay, HIF-1α nuclear translocation assay, and increased VEGF expression.

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