Angustine is a monoterpene indole alkaloid that functions primarily as a vasodilator. It demonstrates significant vasodilatory activity, achieving over 90% vasodilation in isolated rat aorta at a concentration of 10 μM. This compound is suitable for investigating conditions such as hypertension, cerebral vasospasm, and peripheral circulatory disorders. Angustine is naturally derived from the bark of Nauclea officinalis and is also found in several other plant genera, including Mitragyna, Uncaria, and Strychnos.
Angustine is a monoterpene indole alkaloid that functions primarily as a vasodilator. It demonstrates significant vasodilatory activity, achieving over 90% vasodilation in isolated rat aorta at a concentration of 10 μM. This compound is suitable for investigating conditions such as hypertension, cerebral vasospasm, and peripheral circulatory disorders. Angustine is naturally derived from the bark of Nauclea officinalis and is also found in several other plant genera, including Mitragyna, Uncaria, and Strychnos.
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