Fig. 1 · Structure
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ANO1-IN-1
ANO1 Inhibitor
ANO1-IN-1 is a selective inhibitor of the ANO1 channel, exhibiting an IC50 of 2.56 μM for ANO1 and 15.43 μM for ANO2. This compound effectively suppresses the proliferation of glioblastoma cells, making it a valuable tool for research in cancer biology and therapeutic development targeting ion channel pathways. Its specificity for ANO1 suggests potential applications in studying diseases associated with aberrant channel activity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 407587-01-3 |
| Applications | ANO1 Inhibitor |
| Formula | C18H28N2O2S |
| Molecular Weight | 336.49 |
| SMILES | CC(C)(C(NC1=C(C2=C(S1)CC(CC2)C(C)(C)C)C(N)=O)=O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.