Fig. 1 · Structure
Documents & Downloads
Anpirtoline hydrochloride
5-HT Receptor Agonist
Anpirtoline hydrochloride is a selective agonist of the 5-HT1B receptor, exhibiting binding affinities of 28 nM for 5-HT1B, 150 nM for 5-HT1A, and 1.49 μM for 5-HT2 receptors. This compound demonstrates serotonergic activity and displays antinociceptive and antidepressant-like effects. It is valuable for research in neuropharmacology, particularly in studying the role of serotonin receptors in pain modulation and mood disorders.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 99201-87-3 |
| Applications | 5-HT Receptor Agonist |
| Formula | C10H14Cl2N2S |
| Molecular Weight | 265.21 |
| Synonyms | D-16949 hydrochloride |
| SMILES | ClC1=NC(SC2CCNCC2)=CC=C1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.