Anpirtoline hydrochloride is a selective agonist of the 5-HT1B receptor, exhibiting binding affinities of 28 nM for 5-HT1B, 150 nM for 5-HT1A, and 1.49 μM for 5-HT2 receptors. This compound demonstrates serotonergic activity and displays antinociceptive and antidepressant-like effects. It is valuable for research in neuropharmacology, particularly in studying the role of serotonin receptors in pain modulation and mood disorders.
Anpirtoline hydrochloride is a selective agonist of the 5-HT1B receptor, exhibiting binding affinities of 28 nM for 5-HT1B, 150 nM for 5-HT1A, and 1.49 μM for 5-HT2 receptors. This compound demonstrates serotonergic activity and displays antinociceptive and antidepressant-like effects. It is valuable for research in neuropharmacology, particularly in studying the role of serotonin receptors in pain modulation and mood disorders.
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